The Chemistry of Acyl Cyanides

Through improved and novel syntheses, acyl cyanides—especially aliphatic acyl cyanides—have become so readily accessible that numerous synthetic applications present themselves. The present review surveys the development of the chemistry of the acyl cyanides during the last 25 years. The syntheses and most important reaction possibilities of RCOCN are outlined in four large schemes: reactions of the CO‐ and CN‐groups—in each case with preservation of the carbon skeletal framework—as well as acylations with cleavage of cyanide ions.