Synergistic approach of structure-based and ligand-based drug design for the development of selective cannabinod receptor ligands

This is the authors' abstract. We don't add key points for this paper.

Cannabinoid receptors (CB) are G-protein coupled receptors involved in many physiological processes, like learning, appetite, nociception and others. Two subtypes (termed CB1 and CB2) are involved in slightly different processes [1]. Thus, it is important to gain more insight into the the cannabinoid receptor system and the potential effects of cannabinoid therapeutics.