Why the study?
Does a total fast up to 13 days alter lipoprotein lipase activity in subcutaneous adipose tissue in obese subjects?
Population
9 obese subjects
Comparison
Total fast up to 13 days vs Baseline (before fast)
Design
Cohort
Follow-up
up to 13 days
Authors
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Hypothesis-generating for adipose LPL adaptation during fasting; leaves open clinical relevance for lipid management in obesity.
Does a total fast up to 13 days alter lipoprotein lipase activity in subcutaneous adipose tissue in obese subjects?
Total fasting in obese subjects leads to an initial decrease in subcutaneous adipose tissue lipoprotein lipase activity followed by a tendency to recover, alongside persistently elevated serum FFA.
Persson et al. (1970) studied this question.
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