Population
Isolated rat pulmonary artery smooth muscle cells
Comparison
Voltage-clamp depolarizations of varying… vs Control conditions
Design
Preclinical
Authors
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Alerts researchers to K+ accumulation artifacts in vascular electrophysiology; leaves open relevance to intact vessels or clinical settings.
The inward tail current observed after delayed rectifier K+ current activation in rat pulmonary artery cells is caused by a reduction in the transmembrane K+ gradient due to extracellular K+ accumulation.
Sv et al. (1994) studied this question.
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