Population
Primate T9-S1 spinothalamic tract (STT) neurons (n=40)
Comparison
Electrical stimulation of vagal afferents vs Baseline activity / no stimulation
Design
Preclinical
Authors
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Suggests a cardioprotective vagal reflex in this model; leaves open translation to human cardiac conditions.
Cardiopulmonary, but not abdominal, vagal afferent input reduces STT cell activity, suggesting an inhibitory vagal reflex that may protect the heart.
Hobbs et al. (1989) studied this question.
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