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December 25, 2020Electronic physicianOpen Access

A Two-Single-Nucleotide Polymorphism Haplotype in Promoter Region of CYP11B2 Gene Affects Plasma Aldosterone Concentration: A Matched Case-Control Study

Fatemeh Nabizadeh Shabnaz Koochakkhani Hossein Farshidi Zahra Farbood fatemeh kharaee Tasnim Eghbal Eftekhaari Elaheh Farahbakhsh Mahmood Khayatian Azim Nejatizadeh

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Abstract

Background: Aldosterone synthesized by aldosterone synthase plays an imperative role in Renin-Angiotensin-Aldosterone System (RAAS). Evidence suggested that aldosterone synthase gene (CYP11B2) variants are associated with the Essential Hypertension (EH).

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Nabizadeh et al. (2020) studied this question.

synapsesocial.com/papers/6a8b2c340cf18037ebbe94e0 https://doi.org/10.19082/7767

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