The deposition of liver glycogen in starved rats given a single dose of cortisone is inhibited by puromycin and actinomycin. The former agent interferes with induced enzyme formation in general, and the latter with the cortisone-induced rise in liver enzyme levels. The results suggest that the regulatory effect of cortisone on carbohydrate metabolism may be brought about by its action on the cellular concentration of certain enzyme proteins.
No takes yet. Share an insight, caveat, or question.
Greengard et al. (1963) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: