Key result
Carrying a fetus with congenital heart disease was associated with a higher risk of pre-eclampsia compared to a normal population (5.7% vs 1.2%; OR 5.96, 95% CI 3.19-10.54; p<0.0001).
Why the study?
Does carrying a fetus with congenital heart disease increase the risk of placenta-related complications in pregnant women?
Population
279 pregnant women carrying a fetus with congenital heart disease
Comparison
Carrying a fetus with congenital heart disease vs Non-selected pregnant population followed up at…
Design
Cohort
Follow-up
Perinatal period
Authors
Loading...
Supports closer pre-eclampsia monitoring in fetal CHD pregnancies; hypothesis-generating for placental complications, needing prospective validation.
Cohort
No
Does carrying a fetus with congenital heart disease increase the risk of placenta-related complications in pregnant women?
Odds Ratio: 5.96 (95% CI 3.19–10.54)
Absolute Event Rate: 5.7% vs 1.2%
p-value: p=< 0.0001
Women carrying a fetus with congenital heart disease have a significantly higher risk of placenta-related complications, including pre-eclampsia, intrauterine growth restriction, and stillbirth.
Ruiz et al. (2016) conducted a cohort in Pregnancy with fetal congenital heart disease. Fetal congenital heart disease vs. Non-selected pregnant population was evaluated on Pre-eclampsia (OR 5.96, 95% CI 3.19-10.54, p=< 0.0001). Carrying a fetus with congenital heart disease was associated with a higher risk of pre-eclampsia compared to a normal population (5.7% vs 1.2%; OR 5.96, 95% CI 3.19-10.54; p<0.0001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: