January 1, 2000Journal of Magnetic Resonance ImagingOpen Access

Acquired generalized lipoatrophy (AGL): Highly selective MR lipid imaging and localized1H-MRS

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Population

n=6

Comparison

Frequency-selective chemical shift magnetic… vs Age-matched healthy volunteers

Design

Case-control

Authors

KBKlaus BrechtelFranziskus-Krankenhaus Berlin SJStephan JacobClinical Trial Investigators JMJ MachannDeutsches Diabetes-Zentrum e.V.

Discussion

Member takes

Implication

May enable noninvasive lipid quantification in AGL; leaves open validation for clinical monitoring or larger studies.

Structured PICO

Population

n=6 (1 patient with acquired generalized lipoatrophy [AGL; Lawrence syndrome] and 5 age-matched healthy volunteers)

Intervention

Frequency-selective chemical shift magnetic resonance (MR) imaging and (1)H-MRS

Comparator

Age-matched healthy volunteers

Outcome

Assessment of intra- (IMCL) and extramyocellular lipid stores (EMCL) and tissue compositionsurrogate

Chemical shift-selective MR imaging and localized spectroscopy enable noninvasive, quantitative assessment of tissue composition in acquired generalized lipoatrophy.

Cite This Study

Brechtel et al. (2000) studied this question.

synapsesocial.com/papers/6a8b8ff0d5d4290f64f47487 https://doi.org/10.1002/1522-2586(200008)12:2<306::aid-jmri13>3.0.co;2-w

View Full Paper

Ask AI

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Acquired generalized lipoatrophy (AGL): Highly selective MR lipid imaging and localized1H-MRS

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Acquired generalized lipoatrophy (AGL): Highly selective MR lipid imaging and localized1H-MRS

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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Also Consider