Why the study?
Do brain atrophy and lesion volumes predict 10-year clinical evolution and disability in multiple sclerosis?
Population
261 multiple sclerosis patients with MR imaging at baseline and after 1-2 years, and Expanded Disability…
Design
Cohort
Follow-up
10 years
Authors
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May aid long-term MS disability prediction via MRI; extends imaging biomarkers but leaves open prospective validation.
Do brain atrophy and lesion volumes predict 10-year clinical evolution and disability in multiple sclerosis?
Brain atrophy and lesion volumes on MRI have complementary value in predicting long-term (10-year) clinical disability in patients with multiple sclerosis.
Popescu et al. (2013) studied this question.
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