Why the study?
Does processing of cardiotomy blood by centrifugal washing and lipid filtration improve neurocognitive functioning or reduce blood product use in patients undergoing coronary and/or aortic valve surgery using cardiopulmonary bypass?
Population
266 patients undergoing coronary and/or aortic valve surgery using cardiopulmonary bypass.
Comparison
Cardiotomy blood processed by centrifugal… vs Unprocessed cardiotomy blood reinfusion.
Design
RCT, Randomized, Patients and treating physicians were blinded to treatment…
Follow-up
3 months
Authors
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Processing cardiotomy blood increases transfusions without neurocognitive benefit; challenges routine use and supports abandoning the practice in cardiac surgery.
Does processing of cardiotomy blood by centrifugal washing and lipid filtration improve neurocognitive functioning or reduce blood product use in patients undergoing coronary and/or aortic valve surgery using cardiopulmonary bypass?
Processing cardiotomy blood before reinfusion during cardiac surgery increases blood product use and postoperative bleeding without providing neurocognitive benefits.
Rubens et al. (2007) studied this question.
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