This study was carried out on 45 newborns to evaluate the accuracy of 1 minute Apgar score and umbilical arterial pH for prediction of the risk of perinatal brain damage. Using a new and very sensitive method for CK-BB determination, which is considered a good indicator of brain damage, CK-BB was used as reference. Patients with low Apgar score at one minute of life had significantly higher cord blood CK-BB values than the control group (p less than 0.01). No difference was found between the control group and the group with umbilical cord blood acidosis (p less than 0.2).
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Amato et al. (1986) studied this question.
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