Why the study?
Is plasma noradrenaline concentration increased in patients with chronic obstructive lung disease and does it correlate with hemodynamics and blood gases?
Population
9 patients with chronic obstructive lung disease, elevated mean pulmonary arterial pressure, and no clinical…
Comparison
Oxygen inhalation and right heart catheterization vs Normal subjects (for 8-month comparison)
Design
Cohort
Follow-up
8 months
Authors
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May indicate heightened sympathetic activity in hypoxemic COPD; leaves open effects on hemodynamics or outcomes.
Is plasma noradrenaline concentration increased in patients with chronic obstructive lung disease and does it correlate with hemodynamics and blood gases?
Patients with chronic obstructive lung disease exhibit enhanced sympathetic nervous activity, evidenced by elevated plasma noradrenaline that correlates with deranged blood gases.
Henriksen et al. (1980) studied this question.
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