Nucleoside und Nucleotide. Teil 20. Synthese von Desoxyribooligonucleotiden nach der Diester‐ und Triestermethode mit 2(1H)‐Pyrimidinon als Base

Nucleosides and Nucleotides. Part 20, Synthesis of Desoxyribooligonucleotides According to the Diester and Triester Method with 2(1H)‐Pyrimidinone as Base The syntheses of the dinucleosidemonophosphate 1‐(2′‐deoxy‐b̃‐D‐ribofuranosyl)‐2(1H)‐pyrimidinon‐(3′‐5′)‐2′‐deoxycytidine (MdpCd; 4) and the trinucleoside‐diphosphate thymidyl‐(3′‐5′)‐thymidylyl‐(3′‐5′)‐1‐(2′‐deoxy‐b̃‐D‐ribofuranosyl)‐2(1H)pyrimidinon (TdpTdpMd; 1) are described, Compound 1 was synthesized by different variants of the triester method, and 4 by the diester method as well as the triester method.