In erythropoietic mouse cells induced by Friend leukemia virus, approximately 50% of non-polyribosomal globin mRNA is found in 48 S initiation complexes ready to be translated. EDTA releases 15 S globin mRNPs, homologous to polyribosomal globin mRNPs. The 76-kDa poly(A)-protein is one of its main protein components. The other 50% of non-polyribosomal message can be separated as 20 S 'free' mRNPs. Its protein composition is different, especially the 76-kDa protein is lacking. The role of this protein is discussed.
No takes yet. Share an insight, caveat, or question.
Schmid et al. (1983) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: