Why the study?
Does continued OAC therapy reduce bleeding and thromboembolic events compared to heparin bridging or interrupted OAC in patients undergoing CIED implantation?
Population
3,744 patients on chronic oral anticoagulant therapy undergoing cardiac implantable electronic devices…
Comparison
Heparin bridging or interrupted OAC therapy vs Continued OAC therapy
Design
Meta-analysis
Authors
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Favors uninterrupted OAC over heparin bridging for CIED implantation; reinforces guidelines by showing lower bleeding without excess thromboembolism.
Does continued OAC therapy reduce bleeding and thromboembolic events compared to heparin bridging or interrupted OAC in patients undergoing CIED implantation?
Continuous OAC therapy during CIED implantation offers the best balance of safety and efficacy by minimizing bleeding risk without increasing thromboembolic events compared to heparin bridging.
Ling et al. (2014) studied this question.
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