The two-pore domain potassium (K2P) channel family is composed by 15 members, identified in the human genome, and also K2P channels have been identified in yeast, plants, zebrafish, nematode and fruitfly (Goldstein et al., 2001). Based on their primary structure and functional properties, K2P channels are grouped into six distinct subfamilies denoted as TREK, TALK, TASK, TWIK, THIK, and TRESK (Goldstein et al., 2001, 2005; Figure Figure1A1A).
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Zúñiga et al. (2016) studied this question.
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