Population
Xenopus laevis oocytes and mammalian cells
Comparison
Co-expression of TASK-1 and TASK-3 potassium… vs Individual expression of TASK-1 or TASK-3
Design
Preclinical
Authors
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Extends TASK channel diversity in expression systems; leaves open heterodimer roles in native cardiovascular tissue.
Demonstrates that TASK-1 and TASK-3 two-pore domain potassium channels can form functional heterodimers, suggesting a mechanism for greater functional diversity in native tissues.
Czirják et al. (2002) studied this question.
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