March 1, 2000Journal of Biological ChemistryOpen Access

TASK-3, a New Member of the Tandem Pore K+ Channel Family

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Population

Rat cerebellum cDNA library and COS-7 cells expressing TASK-3

Design

Preclinical

Authors

YKYangmi KimDaegu Haany University HBHyoweon BangChung-Ang University DKDonghee KimRosalind Franklin University of Medicine and Science

Discussion

Member takes

Implication

May influence cardiac pH sensing; extends tandem pore K+ family but leaves roles in disease open.

Structured PICO

Population

Rat cerebellum cDNA library and COS-7 cells expressing TASK-3

Intervention

Cloning and expression of TASK-3, mutation of histidine 98 to aspartate, and application of extracellular pH changes, barium, quinidine, and lidocaine

Outcome

Electrophysiological properties and pharmacological sensitivity of the TASK-3 channelsurrogate

The study identifies and characterizes TASK-3 as a novel member of the acid-sensing tandem pore K+ channel family.

Cite This Study

Kim et al. (2000) studied this question.

synapsesocial.com/papers/6a9909c424d3faa49b7498aa https://doi.org/10.1074/jbc.275.13.9340

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TASK-3, a New Member of the Tandem Pore K+ Channel Family

Discussion

Member takes

Implication

Structured PICO

Cite This Study

TASK-3, a New Member of the Tandem Pore K+ Channel Family

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider