Why the study?
Patients with CCTGA are predisposed to AV block, pacing-induced cardiomyopathy, and RV failure, and RV failure may persist despite biventricular CRT or CSP.
Does CSP-optimized CRT improve electrical synchrony and clinical outcomes in patients with CCTGA and intrinsic RV electrical delay compared to conventional CSP?
Does CSP-optimized CRT improve electrical synchrony and clinical outcomes in patients with CCTGA and intrinsic RV electrical delay compared to conventional CSP?
CSP-optimized CRT may provide superior electrical resynchronization and clinical benefit compared to conventional CSP in select patients with CCTGA.
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Conventional CSP may incompletely resynchronize CCTGA with RV delay; leaves open distal CSP or alternatives for prospective study.
Su et al. (2025) studied this question.
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