Why the study?
Diagnosis of von Willebrand disease is difficult and complex because no single test explores all von Willebrand factor activities to confirm or exclude diagnosis.
What are the recent advances in the laboratory diagnosis and classification of von Willebrand disease?
Design
Review
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Advances in VWF assays may refine VWD diagnosis; leaves open standardization and prospective validation before routine use.
What are the recent advances in the laboratory diagnosis and classification of von Willebrand disease?
Novel automated assays and the VWF-collagen binding assay improve the complex laboratory diagnosis and classification of von Willebrand disease, particularly for type 2 variants.
Castaman et al. (2019) studied this question.
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