Population
troponin-regulated thin filaments
Design
Preclinical
Authors
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Does not alter clinical practice; confirms the steric blocking model while leaving open translation to human cardiac thin filaments.
Cryoelectron microscopy confirms the steric blocking model of muscle regulation by resolving the position of tropomyosin on actin filaments under relaxing and activating conditions.
Chen et al. (1999) studied this question.
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