Effect of Ivabradine on Left Ventricular Diastolic Function of Patients With Preserved Ejection Fraction ― Results of the IVA-PEF Study ―

Figures

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  Figure 1.. Results for the primary endpoint; there was no significant change in mitral inflow E and mitral e’ annular velocities (E/e’) from baseline to 3 months of ivabradine administration. The boxes show the interquartile range, with the median value indicated by the horizontal line; whiskers show the range. Values above the box plots are the mean±SD.

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  Figure 2.. Results for the secondary endpoints. There were no significant changes in B-type natriuretic peptide (BNP) or the left atrial volume index (LAVI) from baseline to 3 months of ivabradine administration. However, there was a significant improvement in global longitudinal strain (GLS) from baseline to 3 months. The boxes show the interquartile range, with the median value indicated by the horizontal line; whiskers show the range. Values above the LAVI and GLS box plots are the mean±SD; values above the BNP box plot are the median (interquartile range).