Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 1, 1973Biochemical JournalOpen Access

Reactions of papain and of low-molecular-weight thiols with some aromatic disulphides. 2,2′-Dipyridyl disulphide as a convenient active-site titrant for papain even in the presence of other thiols

View Full Paper
Ask AI
Bookmark
Share

Authors

KBK BrocklehurstUniversity of East AngliaGLG. LittleSt Bartholomew's Hospital

Discussion

Loading...

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

Brocklehurst et al. (1973) studied this question.

synapsesocial.com/papers/6a8bb2a29ac394ad33cab692https://doi.org/10.1042/bj1330067
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The reaction of papain with Ellman's reagent [5,5′-dithiobis-(2-nitrobenzoate) dianion]1972 · 21 citations
  2. 2Kinetics of the reversible reaction of papain with 5,5′-dithiobis-(2-nitrobenzoate) dianion: evidence for nucleophilic reactivity in the un-ionized thiol group of cysteine-25 and for general acid catalysis by histidine-159 of the reaction of the 5-mercapto-2-nitrobenzoate dianion with the papain-5-mercapto-2-nitrobenzoate mixed disulphide1972 · 20 citations
  3. 3The effect of pH on the affinities of enzymes for substrates and inhibitors1953 · 483 citations
  4. 4Kinetic specificity in papain-catalysed hydrolyses1971 · 103 citations