In a review of adverse events associated with childhood vaccines, the Vaccine Safety Committee of the Institute of Medicine (IOM) in 1993 concluded that a causal relationship exists between live-virus measles-mumps-rubella (MMR) vaccination and thrombocytopenia.1 This finding was based on case reports of temporally associated onset of acute thrombocytopenia purpura and MMR vaccination,2,3 population-based surveillance of adverse vaccine reactions in Sweden4 and Finland,5 and demonstrated decreases in platelet concentrations after measles vaccination with the Edmonston B strain.6 The IOM committee also noted that children with prior histories of thrombocytopenia may be at an increased risk of recurrence after MMR vaccination.
No takes yet. Share an insight, caveat, or question.
Vlacha et al. (1996) studied this question.