Why the study?
Does multisite feedback pacing with four widely spaced electrodes improve defibrillation success rate compared to a single electrode in a mathematical model?
Does multisite feedback pacing with four widely spaced electrodes improve defibrillation success rate compared to a single electrode in a mathematical model?
In a mathematical model, multisite feedback pacing with four widely spaced electrodes substantially improves defibrillation success rates compared to a single electrode.
Supports testing of multisite electrode arrays for defibrillation; leaves open clinical translation from this animal model.
A mathematical model of multisite feedback pacing for defibrillation is optimized for electrode spacing and stimulus period. For four electrodes, the defibrillation success rate is highest at 88% when the electrodes are spaced as far apart as possible. For a single electrode, the optimum success rate was 26%.
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Puwal et al. (2008) studied this question.
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