A naturally occurring malignant canine venereal tumor in the vagina of a mature Collie dog did not regress following surgical intervention. The tumor progressed fatally over a period of 5 weeks and metastasized to the inguinal and iliac lymph nodes, spleen, eye, and brain. It had a modal number of 60 chromosomes of which 17 were metacentric.
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Adams et al. (1970) studied this question.
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