Population
Rat skeletal muscles (embryonic, neonatal, adult fast and slow) and cardiac ventricles
Design
Preclinical
Authors
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Distinguishes myosin subfragments across developmental and muscle types in animals; extends isoform mapping but leaves open human cardiac relevance.
This preclinical study demonstrates that structural differences among myosin heavy chain isozymes are located in both the S-1 and rod subfragments.
Bugaisky et al. (1984) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: