Why the study?
Does midazolam with fentanyl improve sedation and analgesia compared to midazolam alone in patients undergoing lower-extremity angiography?
Population
50 patients undergoing lower-extremity angiography
Comparison
Midazolam with fentanyl administered as an IV… vs Midazolam with placebo administered as an IV bolus
Design
RCT, Randomized, Double-blind
Follow-up
8-24 hr after the procedure
Authors
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Supports adding fentanyl to midazolam for superior sedation in lower-extremity angiography; extends evidence for combination regimens in interventional procedures.
Does midazolam with fentanyl improve sedation and analgesia compared to midazolam alone in patients undergoing lower-extremity angiography?
The addition of fentanyl to midazolam improves sedation and analgesia during lower-extremity angiography without significant adverse hemodynamic effects.
Cragg et al. (1991) studied this question.
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