November 3, 2010Cells Tissues Organs

Spatiotemporal Localization of Periostin and Its Potential Role in Epithelial-Mesenchymal Transition during Palatal Fusion

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Population

Mouse model of palatal fusion

Design

Preclinical

Authors

YKYukiko KitaseIndiana University Health KYKeisuke YamashiroKyushu University KFKatherine FuUniversity of British Columbia

Discussion

Member takes

Implication

Hypothesis-generating for periostin in palatal EMT; leaves open human cleft palate relevance.

Structured PICO

Population

Mouse model of palatal fusion

Intervention

Evaluation of spatiotemporal expression patterns of periostin by in situ hybridization and immunofluorescence

Outcome

Spatiotemporal expression patterns of periostin and its association with EMT markers during palatal fusionsurrogate

Periostin expression in the basement membrane and select medial edge epithelia suggests it plays a role in regulating epithelial-mesenchymal transition during palatal fusion.

Cite This Study

Kitase et al. (2010) studied this question.

synapsesocial.com/papers/6a8bce149d5fb440a3beb9d5 https://doi.org/10.1159/000320178

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Spatiotemporal Localization of Periostin and Its Potential Role in Epithelial-Mesenchymal Transition during Palatal Fusion

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Spatiotemporal Localization of Periostin and Its Potential Role in Epithelial-Mesenchymal Transition during Palatal Fusion

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider