Why the study?
Does echocardiography help in assessing the etiology and operability of clinically suspected severe ischaemia-induced mitral regurgitation?
Does echocardiography help in assessing the etiology and operability of clinically suspected severe ischaemia-induced mitral regurgitation?
Echocardiography is valuable for differentiating non-ischaemic from ischaemic causes of severe mitral regurgitation and identifying patients with operable lesions versus those with extensive myocardial injury and high surgical risk.
May support echocardiography for MR differentiation in limited cases; leaves open broader validation before clinical adoption.
Eighteen patients with clinical signs suggesting severe mitral regurgitation secondary to ischaemic heart disease were assessed by echocardiography. Non-ischaemic diseases needing specific therapy were revealed in six patients. In the other 12 patients echocardiography demonstrated myocardial lesions explaining the mitral regurgitation. Apart from the distinction between non-ischaemic conditions and lesions induced by ischaemia, echocardiography seems to be helpful in the demonstration of severe yet operable mitral valve regurgitation due to a small ischaemic lesion. Such cases are opposed to functional mitral regurgitation caused by extensive myocardial injury as demonstrated by two-dimensional echocardiography and reflected by a minimum mitral valve/septum separation of more than 2 1/2 cm on the M-mode echocardiogram. These conditions make symptomatic improvement by mitral valve surgery unlikely and carry an extremely high operative mortality. A more precise definition by heart catheterization is required when serious clinical heart failure is not explained by the echocardiographic finding of severe global myocardial impairment.
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Egeblad et al. (1984) studied this question.
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