November 9, 1964JAMA

Mitral Valvular Disease: Hemodynamic Studies of the Consequences for the Circulation

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Structured PICO

Population

250 patients, most with mild mitral stenosis, studied in Sweden over a 15-year period from 1948 through 1962.

Intervention

Hemodynamic studies including exercise, antihypertensive drugs, renal function testing, and cardiac catheterization; operation in 38 patients.

Outcome

Hemodynamic responses to stressful procedures, medication, and operation.surrogate

This book provides a detailed historical cohort of hemodynamic data on patients with mitral stenosis over a 15-year period.

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Historical mitral stenosis hemodynamics provide reference benchmarks; extends observational data but should not yet inform contemporary management.

Robert L. Grissom (1964) studied this question.

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Historical mitral stenosis hemodynamics provide reference benchmarks; extends observational data but should not yet inform contemporary management.