Hemodynamic Studies Before and After Instrumental Mitral Commissurotomy
Why the study?
Does instrumental mitral commissurotomy improve hemodynamic parameters in patients with mitral stenosis?
Population
35 patients with mitral stenosis
Comparison
Instrumental mitral commissurotomy vs Pre-operative baseline
Design
Cohort
Follow-up
at least 6 months
Authors
Discussion
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Member takes
Implication
Supports hemodynamic gains from commissurotomy in mitral stenosis; leaves open optimal selection and durability pending prospective trials.
Structured PICO
Does instrumental mitral commissurotomy improve hemodynamic parameters in patients with mitral stenosis?
P
Population
35 patients with mitral stenosis (8 with concomitant mild or moderate preoperative aortic insufficiency, some with atrial fibrillation)
I
Intervention
Instrumental mitral commissurotomy
C
Comparator
Pre-operative baseline (before-and-after comparison)
O
Outcome
Changes in calculated mitral valve area, cardiac index, and pulmonary vascular resistancesurrogate
Instrumental mitral commissurotomy significantly improves mitral valve area and hemodynamics in patients with mitral stenosis, particularly in younger patients and those achieving an area increase over 1.0 cm2.
Limitations
- Could not determine whether poorer results in patients with atrial fibrillation were a result of age or the arrhythmia
Cite This Study
Feigenbaum et al. (1968) studied this question.