What does this research mean for the field?

Percutaneous balloon mitral valvuloplasty significantly increases mitral valve area and improves hemodynamic parameters in symptomatic mitral stenosis, although Doppler echocardiography correlates only moderately with catheterization measurements in the peri-procedural setting. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

April 1, 1988The American Journal of CardiologyOpen Access

Noninvasive assessment of mitral stenosis before and after percutaneous balloon mitral valvuloplasty

Q: What are the key findings of this study?

The presence of mitral annular calcification was associated with a significantly lower likelihood of achieving an optimal immediate result following percutaneous transvenous mitral commissurotomy (OR 0.154).

Q: What is the clinical evidence from this study?

Study design: Cohort. Population: Rheumatic mitral stenosis (n=87). Intervention: Mitral annular calcification vs. Normal mitral annulus. Primary outcome: Optimal PTMC result (mitral valve area ≥ 1.5 cm2 or ≥25% increase without post-procedure MR grade > 2) (OR 0.154, 95% CI 0.038-0.626, p=<0.01).

View Full Paper

Ask AI

Bookmark

Key result

Mitral annular calcification is linked to an ~85% lower likelihood of optimal PTMC results.

OR 0.154
95% CI 0.038-0.626
P<0.01
n=87

Why the study?

Noninvasive assessment of mitral stenosis before and after percutaneous balloon mitral valvuloplasty requires evaluation to understand changes in valve area and hemodynamics.

Comparison

Before and after balloon mitral valvuloplasty

Design

Observational study

Authors

PCPatricia C. ComeHarvard Vanguard Medical Associates MRMarilyn F. RileyBeth Israel Deaconess Medical Center DDDaniel J. DiverUniversity of Connecticut

Discussion

Member takes

Implication

Study Design

Type

Cohort (n=87)

Multicenter

PICO

Population

87 patients with rheumatic mitral stenosis undergoing percutaneous transvenous mitral commissurotomy, evaluated retrospectively to assess the impact of mitral annular calcification on immediate procedural success.

Exposure / Comparator

Mitral annular calcification vs Normal mitral annulus

Primary Outcome

Optimal PTMC result (mitral valve area ≥ 1.5 cm2 or ≥25% increase without post-procedure MR grade > 2) — OR 0.154 (0.038-0.626), p=<0.01

Main Result

Odds Ratio: 0.154 (95% CI 0.038–0.626)

Absolute Event Rate: 29.4% vs 71.4%

p-value: p=<0.01

Limitations

Morphological abnormalities may have been underestimated through the use of transthoracic echocardiography since three-dimensional structures were evaluated in two-dimensions.
Findings on the role of MAC in the PTMC outcome could not be generalized to the late PTMC result.
Retrospective study design.

Cite This Study

Come et al. (1988) conducted a cohort in Rheumatic mitral stenosis (n=87). Mitral annular calcification vs. Normal mitral annulus was evaluated on Optimal PTMC result (mitral valve area ≥ 1.5 cm2 or ≥25% increase without post-procedure MR grade > 2) (OR 0.154, 95% CI 0.038-0.626, p=<0.01). The presence of mitral annular calcification was associated with a significantly lower likelihood of achieving an optimal immediate result following percutaneous transvenous mitral commissurotomy (OR 0.154).

synapsesocial.com/papers/6ac327ee49fbb9608ef7aa5f https://doi.org/10.1016/0002-9149(88)91073-9

Topics

Echocardiography

View Full Paper

Ask AI

Bookmark

Noninvasive assessment of mitral stenosis before and after percutaneous balloon mitral valvuloplasty

Discussion

Member takes

Implication

Study Design

PICO

Main Result

Limitations

Cite This Study

Topics

Noninvasive assessment of mitral stenosis before and after percutaneous balloon mitral valvuloplasty

Discussion

Member takes

Implication

Study Design

PICO

Main Result

Limitations

Cite This Study

Also Consider

Topics

Also Consider