Key result
Percutaneous balloon valvuloplasty in patients with mild mitral stenosis significantly increased valve area from 1.7 to 3.1 cm2 (p<0.0001), with no progression of mitral regurgitation.
Why the study?
Does percutaneous balloon valvuloplasty improve hemodynamics and clinical outcomes in patients with mild mitral stenosis?
Population
288 patients with mitral stenosis, specifically focusing on a subgroup of 21 patients with mild mitral…
Comparison
Percutaneous balloon valvuloplasty vs 267 patients with more severe mitral stenosis…
Design
Cohort
Follow-up
22 +/- 12 months
Authors
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Supports early valvuloplasty consideration in selected mild mitral stenosis; hypothesis-generating for randomized outcome trials.
Cohort (n=288)
Does percutaneous balloon valvuloplasty improve hemodynamics and clinical outcomes in patients with mild mitral stenosis?
Absolute Event Rate: 3.1% vs 1.98%
p-value: p=<0.0001
Early percutaneous balloon valvuloplasty significantly increases valve area and maintains functional status without major complications in selected patients with mild rheumatic mitral stenosis.
Pan et al. (1991) conducted a cohort in Mitral stenosis (n=288). Percutaneous balloon valvuloplasty vs. Patients with more severe mitral stenosis (basal area <1.5 cm2) was evaluated on Final mitral valve area (p=<0.0001). Percutaneous balloon valvuloplasty in patients with mild mitral stenosis significantly increased valve area from 1.7 to 3.1 cm2 (p<0.0001), with no progression of mitral regurgitation.
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