Why the study?
Is the titin (TTN) gene associated with endurance training-induced changes in submaximal exercise stroke volume?
Is the titin (TTN) gene associated with endurance training-induced changes in submaximal exercise stroke volume?
The titin (TTN) gene is a strong candidate for explaining interindividual differences in cardiac adaptation, specifically stroke volume response, to endurance training.
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TTN linkage suggests possible genetic influence on stroke volume adaptation; leaves open replication before any clinical relevance.
Rankinen et al. (2003) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: