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April 1, 1923Archives of Internal Medicine

Clinical Experience With Quinidin

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Why the study?

Does quinidine sulphate improve circulation efficiency in patients with auricular fibrillation?

Population

16 patients with auricular fibrillation

Design

Case_series

Authors

CBC. Sidney BurwellBrigham and Women's Hospital

Discussion

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Implication

Historical case series on quinidine in AF leaves open whether rhythm restoration improves circulation efficiency; modern prospective trials needed.

Structured PICO

Does quinidine sulphate improve circulation efficiency in patients with auricular fibrillation?

P
Population
16 patients with auricular fibrillation
I
Intervention
Quinidine sulphate (administered after rest and, in most cases, thorough digitalization)
O
Outcome
Improvement in efficiency of the circulation following restoration of normal rhythm (judged by subjective and objective criteria)

This historical case series evaluates whether restoring normal rhythm with quinidine improves circulation efficiency in patients with auricular fibrillation.

Cite This Study

C. Sidney Burwell (1923) studied this question.

synapsesocial.com/papers/6a8bd8a895f0361a9ebee759https://doi.org/10.1001/archinte.1923.00110160065004
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1CLINICAL STUDIES OF QUINIDIN1922 · 27 citations
  2. 2CLINICAL STUDIES OF QUINIDIN1923 · 3 citations
  3. 3AURICULAR FIBRILLATION1929 · 23 citations
  4. 4Quinidine Therapy of Chronic Auricular Fibrillation1963 · 86 citations
  5. 5Experimental studies of the pharmacology of quinidin1921 · 21 citations