Why the study?
Does autonomic nervous system activity predict cardiovascular and cerebrovascular events and death in an elderly general population?
Population
1,011 elderly subjects from the general population of Saint-Etienne, France, mean age 65.6 (0.8) years.
Design
Cohort
Follow-up
7 years (2001-2007) plus late events monitoring
Authors
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Does not yet guide risk stratification; leaves open whether ANS activity predicts CV events in the elderly.
Does autonomic nervous system activity predict cardiovascular and cerebrovascular events and death in an elderly general population?
The PROOF study established a cohort of 1,011 elderly subjects to prospectively evaluate autonomic nervous system activity as a predictor of cardiovascular events and mortality.
Barthélemy et al. (2007) studied this question.
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