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July 3, 1992Science

An Unlikely Sugar Substrate Site in the 1.65 Å Structure of the Human Aldose Reductase Holoenzyme Implicated in Diabetic Complications

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Authors

DWDavid K. WilsonArkansas Children's HospitalKBKurt M. BohrenBaylor College of MedicineKGKenneth H. GabbayBaylor College of Medicine

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Wilson et al. (1992) studied this question.

synapsesocial.com/papers/6a8bda5bf71fc1553cbeabe5https://doi.org/10.1126/science.1621098
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Aldo-Keto Reductase Superfamily1989 · 455 citations
  2. 2Anatomy of a Conformational Change: Hinged "Lid" Motion of the Triosephosphate Isomerase Loop1990 · 286 citations
  3. 3A novel type of crystallin in the frog eye lens1984 · 73 citations
  4. 4The Pharmacology of Aldose Reductase Inhibitors1985 · 212 citations
  5. 5Purification and Characterization of Human‐Brain Aldose Reductase1982 · 139 citations