Patients with hereditary thrombosis require lifelong anticoagulation to prevent thrombotic events and reduce mortality.
May support lifelong anticoagulation in hereditary thrombosis; leaves open randomized confirmation of mortality benefit.
Recognition of patients who should be evaluated for either hereditary or acquired hypercoagulable states is important so that treatment may be instituted if necessary to prevent thrombosis. Close attention to the medical history, medications, family history, and circumstantial risk factors can help identify patients at risk so that morbidity and mortality may be reduced. Patients with hereditary thrombosis should receive lifelong anticoagulation.
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Bowen et al. (1992) studied this question.
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