Genetic disruption or prolonged chemical inhibition of COX-1 and COX-2 decreases recovery of left ventricular function after ischemia, suggesting a protective role of COX or its metabolites.
No takes yet. Share an insight, caveat, or question.
Impaired post-ischemic LV recovery in COX-1/2 knockout mice; leaves open whether COX inhibition affects human myocardial outcomes.
Camitta et al. (2001) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: