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April 1, 1996BJOG An International Journal of Obstetrics & Gynaecology

Hepatitis C virus infection in pregnancy

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Population

1700 consecutive pregnant women, including 29 (1.7%) who were anti-HCV positive

Design

Cohort

Follow-up

six months after delivery

Authors

AFAnnarosa FloreaniDPDelia M. PaternosterFZF. Zappalà

Discussion

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Overview

Reassures on HCV management in pregnancy; hypothesis-generating and requires larger prospective validation.

Structured PICO

P
Population
1700 consecutive pregnant women, including 29 (1.7%) who were anti-HCV positive
O
Outcome
Clinical aspects of HCV liver disease during pregnancy and six months after delivery, and pregnancy outcome

HCV infection in pregnant women does not appear to worsen liver disease, nor does it increase the risk of obstetric complications.

Cite This Study

Floreani et al. (1996) studied this question.

synapsesocial.com/papers/6a8be272fd375bdc37f44f6fhttps://doi.org/10.1111/j.1471-0528.1996.tb09736.x
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Alpha interferon in human pregnancy1986 · 93 citations
  2. 2Unusually large interferon-α-like mRNAs and high expression of interleukin-6 in human fetal annexes1989 · 28 citations
  3. 3Mother-to-Child Transmission of Hepatitis C Virus Detected by Nested Polymerase Chain Reaction1992 · 157 citations
  4. 4Lack of mother-to-infant transmission of hepatitis C virus in human immunodeficiency virus-seronegative women: A prospective study with hepatitis C virus RNA testing1993 · 137 citations