Pleconaril and intravenous immunoglobulin may be an effective management strategy for acute flaccid paralysis syndrome associated with echovirus 19 in immunocompromised patients.
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May warrant trial in refractory echovirus AFP among immunocompromised hosts; hypothesis-generating and requires prospective validation.
We describe a 39-year-old woman who had undergone bilateral lung and renal transplantation and who was admitted to the hospital with acute onset of flaccid paralysis of the left leg due to echovirus 19 infection. The patient was treated with pleconaril and intravenous immunoglobulin, which correlated with clinical and laboratory evidence of improvement.
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Starlin et al. (2001) studied this question.
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