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January 1, 2023TNOA Journal of Ophthalmic Science and ResearchOpen Access

A clinico-virological study on identification of viral aetiological agents in conjunctivitis

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Why the study?

The study was conducted to identify and isolate viral aetiological agents causing conjunctivitis among outpatients with suspected viral conjunctivitis or keratoconjunctivitis, and to correlate clinical symptomatology with the isolated virus.

Population

75 patients with conjunctivitis of suspected viral aetiology at a tertiary eye care hospital in Chennai

Authors

NFNirmal FredrickGovernment Hospital of Thoracic MedicineSNSunitha NirmalKKKaveri KrishnasamyKing Institute of Preventive Medicine and Research

Discussion

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Implication

Supports regional surveillance; leaves open whether viral typing should guide therapy or trials.

Structured PICO

P
Population
75 patients (age ranging from 6 to 82 years; mean age: 37.3 years) with conjunctivitis of suspected viral aetiology attending an outpatient department at a tertiary eye care hospital in Chennai
I
Intervention
Viral isolation using virus-susceptible cell lines and molecular diagnosis by real-time PCR from conjunctival swabs
O
Outcome
Identification and isolation of viral aetiological agents

Adenovirus is the most common viral pathogen causing conjunctivitis in this cohort, with a notable rate of viral co-infections.

Cite This Study

Fredrick et al. (2023) studied this question.

synapsesocial.com/papers/6a8be68be066a6a97ec45cd2https://doi.org/10.4103/tjosr.tjosr_92_22
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1General primer-mediated polymerase chain reaction for detection of enteroviruses: application for diagnostic routine and persistent infections1992 · 344 citations
  2. 2Outbreak of acute hemorrhagic conjunctivitis in Maharashtra and Gujarat states of India, caused by coxsackie virus A‐24 variant2007 · 37 citations
  3. 3Clinical features and treatment of adenovirus infections2008 · 257 citations