October 5, 2018Journal of Medical VirologyOpen Access

Compared to children infected with HAdV-3 alone, those infected with HAdV-7 alone had an increased frequency of severe pneumonia (32.4% vs 11.6%; P=0.031) and higher intensive care unit admission rates (26.5% vs 7.0%; P=0.019).

View Full Paper

Ask AI

Bookmark

Population

4,751 children hospitalized with acute lower respiratory tract infections at Hunan Provincial People's…

Design

Cohort

Authors

LXLe‐Yun XieHunan Normal University BZBing ZhangUniversity of Southern California NXNi‐Guang XiaoHunan Normal University

Discussion

Member takes

Overview

May warrant closer monitoring for HAdV-7 in children; leaves open whether serotype guides therapy.

Structured PICO

Population

4,751 children hospitalized with acute lower respiratory tract infections (ALRTIs) at Hunan Provincial People's Hospital from September 2007 to March 2014, with 93.3% of HAdV-positive patients being younger than 5 years.

Outcome

Genotypes of circulating human adenovirus (HAdV) strains and their associations with clinical symptoms

HAdV-7 is associated with more severe clinical outcomes, including higher rates of severe pneumonia and ICU admission, compared to HAdV-3 in children with lower respiratory tract infections.

Cite This Study

Xie et al. (2018) studied this question.

synapsesocial.com/papers/6a8be68ceffeb02058b1edc6 https://doi.org/10.1002/jmv.25333

View Full Paper

Ask AI

Bookmark

October 5, 2018Journal of Medical VirologyOpen Access

Compared to children infected with HAdV-3 alone, those infected with HAdV-7 alone had an increased frequency of severe pneumonia (32.4% vs 11.6%; P=0.031) and higher intensive care unit admission rates (26.5% vs 7.0%; P=0.019).

View Full Paper

Ask AI

Bookmark

Population

4,751 children hospitalized with acute lower respiratory tract infections at Hunan Provincial People's…

Design

Cohort

Authors

LXLe‐Yun XieHunan Normal University BZBing ZhangUniversity of Southern California NXNi‐Guang XiaoHunan Normal University

Discussion

Member takes

Overview

May warrant closer monitoring for HAdV-7 in children; leaves open whether serotype guides therapy.

Structured PICO

Population

Outcome

Genotypes of circulating human adenovirus (HAdV) strains and their associations with clinical symptoms

HAdV-7 is associated with more severe clinical outcomes, including higher rates of severe pneumonia and ICU admission, compared to HAdV-3 in children with lower respiratory tract infections.

Cite This Study

Xie et al. (2018) studied this question.

synapsesocial.com/papers/6a8be68ceffeb02058b1edc6 https://doi.org/10.1002/jmv.25333

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

View Full Paper

Ask AI

Bookmark