January 18, 2006Journal of Medical Virology

Genetic heterogeneity of the hexon gene of adenovirus type 3 over a 9-year period in Korea

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Population

29 epidemiologically unrelated adenovirus type 3 isolates from 7 genome types associated with childhood…

Design

Preclinical

Authors

ECEun Hwa ChoiEwha Womans University HKHee Sup KimDongguk University KPKi Ho ParkSeoul National University

Discussion

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Implication

Ad3 hexon heterogeneity may affect antigenicity; leaves open effects on human disease severity or vaccine response.

Structured PICO

Population

29 epidemiologically unrelated adenovirus type 3 (Ad3) isolates from 7 genome types associated with childhood pneumonia in Korea during the period 1991-1999

Intervention

Hexon sequence analysis

Outcome

Genetic heterogeneity and amino acid changes in the hexon genesurrogate

Genetic heterogeneity in the Ad3 hexon gene, particularly in loop 2, is associated with the emergence of new genome types and altered hydropathic characteristics.

Cite This Study

Choi et al. (2006) studied this question.

synapsesocial.com/papers/6a8be7900c58d86fb4cae56c https://doi.org/10.1002/jmv.20550

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Genetic heterogeneity of the hexon gene of adenovirus type 3 over a 9-year period in Korea

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Genetic heterogeneity of the hexon gene of adenovirus type 3 over a 9-year period in Korea

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider