Site‐directed chemical conversion of serine to cysteine in penicillin acylase from Escherichia coli ATCC 11105

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Reactivities of the various protonic states in the reactions of papain and of L-cysteine with 2,2′- and with 4,4′- dipyridyl disulphide: evidence for nucleophilic reactivity in the un-ionized thiol group of the cysteine-25 residue of papain occasioned by its interaction with the histidine-159-asparagine-175 hydrogen-bonded system1972 · 71 citations
2. 2The Reactivity of Thiol-subtilisin, an Enzyme Containing a Synthetic Functional Group^*1967 · 124 citations
3. 3The Thiol Groups of Fumarase1967 · 66 citations
4. 4Reactions of papain and of low-molecular-weight thiols with some aromatic disulphides. 2,2′-Dipyridyl disulphide as a convenient active-site titrant for papain even in the presence of other thiols1973 · 161 citations
5. 5Ionisation Constants of Some Penicillins and of their Alkaline and Penicillinase Hydrolysis Products1963 · 55 citations