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Right-sided infective endocarditis (RSIE) secondary to central venous catheter (CVC) infection is traditionally treated with prolonged antimicrobial therapy and, in selected cases, cardiac surgery. Percutaneous mechanical aspiration (PMA) has emerged as a less invasive adjunctive therapeutic option in selected patients. We describe a 43-year-old man with a large right atrial/tricuspid valve vegetation from CVC infection treated with antimicrobials and PMA, achieving ∼80% vegetation reduction with continued regression on follow-up transesophageal echocardiography. The patient remained asymptomatic with negative blood cultures post-procedure and at 6 months. This case adds to the evidence supporting PMA as an adjunctive treatment for CVC-associated RSIE.
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Stanford et al. (2026) studied this question.
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