Gentamicin was shown to be a highly active inhibitor of growth of clinical isolates of Mycobacterium tuberculosis and other mycobacteria in vitro. Activity was independent of susceptibility or resistance of the microorganisms to commonly used antituberculous agents. At a comparable dosage, gentamicin was weakly tuberculostatic and less efficacious than streptomycin in treatment of mice infected with M. tuberculosis H37Rv. Since gentamicin possesses antituberculous activity, administration of the drug to patients for other purposes may possibly impede recovery of mycobacteria from clinical specimens. Further investigation of the antituberculous activity of gentamicin appears warranted.
No takes yet. Share an insight, caveat, or question.
Sanders et al. (1971) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: