July 26, 2011Journal of Cardiovascular Medicine
Predicting mortality and hospital admission in patients with COPD
Why the study?
Does NT-proBNP predict mortality and hospitalization in patients with COPD?
Population
140 consecutive patients aged at least 18 years with chronic obstructive pulmonary disease (COPD)
Design
Cohort
Follow-up
median 3.9 years
Authors
Discussion
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Member takes
Implication
NT-proBNP does not independently predict COPD survival after adjustment; leaves open its incremental value beyond cardiac comorbidities.
Structured PICO
Does NT-proBNP predict mortality and hospitalization in patients with COPD?
P
Population
140 consecutive patients aged at least 18 years with chronic obstructive pulmonary disease (COPD)
I
Intervention
N-terminal pro-brain natriuretic peptide (NT-proBNP) measurement
O
Outcome
Mortality and hospitalizationhard clinical
NT-proBNP predicts survival in COPD patients, but its prognostic value is superseded by the presence of structural heart disease such as a dilated left atrium, aortic stenosis, and left-ventricular systolic dysfunction.
Cite This Study
Gale et al. (2011) studied this question.